MG is a chronic autoimmune disorder where antibodies block or destroy neuromuscular junction receptors, leading to muscle weakness. This weakness tends to worsen with repeated activity and improves with rest, which helps distinguish MG from other neurological conditions.

Early signs of Myasthenia Gravis often start with eye-related symptoms such as drooping eyelids (ptosis) or double vision (diplopia). As the disease progresses, patients may notice weakness in the face, neck, arms, or legs, as well as trouble swallowing, chewing, or speaking clearly. In generalized Myasthenia Gravis, symptoms can affect multiple muscle groups, while ocular Myasthenia Gravis typically remains limited to the eyes.

MG often progresses gradually, though symptom intensity can fluctuate from day to day. “End-stage” MG is rare thanks to effective modern treatments. However, late-onset MG may appear more suddenly and require ongoing management to prevent complications such as breathing difficulty or aspiration.

Diagnosing Myasthenia Gravis involves a combination of clinical exams and specialized testing. Your neurologist may order:

• Blood tests to detect acetylcholine receptor (AChR) or muscle-specific kinase (MuSK) antibodies
• Electromyography (EMG) to measure the electrical activity between nerves and muscles
• Edrophonium (Tensilon) test to assess immediate muscle response
• CT or MRI scans to check for thymus abnormalities or thymoma

At the MS & Neuromuscular Center of Excellence, our neurophysiology team uses advanced EMG testing and antibody panels to confirm diagnosis and determine the most effective treatment approach.

There is no cure for Myasthenia Gravis, but treatments can effectively control symptoms and improve muscle strength. The best plan depends on your age, overall health, and severity of symptoms.

Common options include:

• Medications: Cholinesterase inhibitors (Mestinon), immunosuppressants (prednisone, azathioprine)
• Plasmapheresis or IVIG (for severe cases)
• Thymectomy (surgical removal of the thymus gland if needed)

Most people with Myasthenia Gravis live active, fulfilling lives with proper treatment and lifestyle adjustments. Managing MG often involves balancing medication schedules, avoiding overexertion, reducing stress, and preventing infections that could trigger flare-ups.

Complications like Myasthenic Crisis—severe muscle weakness that affects breathing—are rare but require emergency care. With consistent medical follow-up and personalized treatment, patients can maintain normal life expectancy and stable symptom control.

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Yes, some patients experience remission with treatment, especially after thymectomy.

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In rare cases, myasthenic crisis (severe breathing difficulty) can occur, requiring emergency care.

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Our experienced staff is dedicated to helping you access patient assistance programs to ensure you receive the care and treatment you need, making healthcare more affordable and accessible. We're here to guide you through the process and connect you with the resources that can support your treatment journey.

Myasthenia Gravis is not inherited or contagious. It generally develops later in life when the immune system mistakenly attacks the body’s own acetylcholine receptors on muscle cells, interfering with muscle contraction. In some cases, temporary Myasthenia Gravis can occur in newborns when antibodies from a mother with MG pass through the placenta, but symptoms usually disappear within a few weeks after birth.